Rutin is widely found in nature and is almost contained in all of the Rutaceae and Sectaceae plants, especially abundant in Rutaceae, Rutaceae, Epacridaceae of leguminous, buckwheat of Polygonaceae, Eulali of Hypericum, Berchemia polyphylla var. leioclada of Tetranychidae, and wild wutong leaves of thistle, which are also used as raw materials in rutin extraction. In addition, it also exists in the Ilex pubescens of Aquifoliaceae, Forsythia of Oleaceae, pagoda tree pod of Leguminosae, tobacco, jujube, apricots, flavedo, tomatoes, and other plants.
At present, rutin in China mainly extracted from the Sophora japonica Linn of leguminous, which is listed in top grade of Shen Nong’s Classic Materia Medica. In addition, tartary buckwheat, which is rich in rutin and flavonoids, is native to India and now produced in China’s northwest, southwest, north, south, and other places.

The inhibitory effect of rutin on lipid peroxidation is related to the enhancement of SOD activity and the promotion of oxygen free radical scavenging. Xia Weimu et al. found that rutin had a strong scavenging effect on O2-, and the scavenging efficiency could reach more than 96%. As a chelating agent of Fe2+, rutin can inhibit Fenton reaction and lipid peroxidation chain reaction and has obvious anti-lipid peroxidation effect. Many kinds of rutin health food have been developed abroad. Sophora japonica has strong antioxidant effect on edible oil. The free radical scavenging rate of sophosa japonica extract can reach 40% ~ 70%, which can be used as a new edible oil and fat food additive with health care function Chemicalbook, and can also be used in cold drinks, beverages, cakes, meat processing products and aquatic products. Tartary buckwheat rutin health care factor has the function of lowering blood lipid, blood pressure, urine sugar and weight loss, and has been developed into delicious and convenient snacks (Tartary buckwheat tea, Tartary buckwheat rice, Tartary buckwheat noodles, etc.). Rutin was hydrolyzed with 2% dilute H2SO4 for 1h, cooled, filtered and precipitated, washed and dried, and refined quercetin was obtained by recrystallization with ethanol. Other flavonoids such as quercetin can be combined with alpha tocopherol, or catechins, to show additive effects.