China (Mainland)
Top Purity Benzocaine 94-09-7 On Sale Factory Supply CAS NO.94-09-7
- Min.Order: 25 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Product Details
Keywords
- lip-soluble?anesthetic
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Quick Details
- ProName: Top Purity Benzocaine 94-09-7 On Sale ...
- CasNo: 94-09-7
- Molecular Formula: C9H11NO2
- Appearance: Crystalline Powder
- Application: API
- DeliveryTime: Prompt Shippment
- PackAge: Drum
- Port: chinese main ports
- ProductionCapacity: Metric Ton/Day
- Purity: 99%
- Storage: 2-8°C
- Transportation: FOB, CIF, CPT
- LimitNum: 25 Kilogram
Superiority
We have several production sites which allow us to produce all of our products on regular basis.
We have a team of researchers and technicians, that constantly devote themselves in developing new products.
Our product quality is stable with many years of production experience accumulation.
Our sales team quotes as per client’s requirements with multilingual speakers of fast response.
We provide fast and safe delivery. We have international logistics services and can deliver services from major
China ports and to client’s designated airport or even to door with custom clearing services.
We provide a range of supportive payment methods from T/T to L/C, which caters to clients with different financial situations and be as supportive as we can.
We have customized packing and reliable storage conditions. We deliver to you freshly made high quality materials and our staff are committed in meeting different packaging requirements as well.
We provide good after-sales service. If there’s any problem with receiving our products, either material-wise, package-wise or shipment-wise, you can come to our sales service team. We will not hold back in answering any questions that you have.
Details
Top Purity Benzocaine 94-09-7 On Sale Factory Supply
Description
Benzocaine is a white needle-like crystal with a melting point of 90-92℃. It is slightly soluble in water and easily soluble in organic solvents. Such as: ethanol, chloroform, ether, soluble in almond oil, olive oil. As a non-aqueous Chemicalbook local anesthetic, benzocaine has analgesic and antipruritic effects. It is clinically used in wound anesthesia, ulcer anesthesia, mucosal surface anesthesia and hemorrhoid anesthesia. Its pharmacological effect is mainly to block nerve endings to relieve pain and itching.
Properties
| Benzocaine Chemical Properties |
| Melting point | 88-90 °C |
| Boiling point | 172 °C (12.7517 mmHg) |
| density | 1.17 |
| refractive index | 1.5600 (estimate) |
| Fp | 172°C/13mm |
| storage temp. | 2-8°C |
| solubility | alcohol: soluble1 gm in 5 ml |
| pka | 2.5(at 25℃) |
| form | Crystalline Powder |
| color | White |
| Water Solubility | Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water |
| Merck | 14,1086 |
| BRN | 638434 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | BLFLLBZGZJTVJG-UHFFFAOYSA-N |
| CAS DataBase Reference | 94-09-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 4-amino-, ethyl ester(94-09-7) |
| EPA Substance Registry System | Benzocaine (94-09-7) |
Application
1. Benzocaine is a local anaesthetic of the ester type with a poor solubility in water. The drug benzocaine is normally used as a topical pain reliever or as a common ingredient in cough drops. Benzocaine is used in multiple forms including lotion, gel, liquid, lozenges, and sprays. When Benzocaine is applied in any form it temporarily numbs or blocks the nerve endings, which leads to a decreases in the amount of pain. It is used in cattle, sheep, swine and horses for local and prolonged low epidural anaesthesia. Standard therapeutic doses of benzocaine ranged from 150 to 750 mg per animal. Benzocaine is also currently used as surface anaesthetic as ointments (0.5% benzocaine) for wounds and ulcerated surfaces in horses, cattle and sheep applied twice a day until healing.
2. A commonly used topical pain reliever. Main active ingredient in anesthetic ointments.
3. Anesthetic;Na+ channel blocker
4. Benzocaine acts on the central nervous system, cardiovascular system, neuromuscular junctions and ganglion synapse. Its mechanism of action is to prevent the generation and conduction of the nerve impulse. Local anaesthetics block conduction by decreasing or preventing the large transient increase in the permeability of excitable membranes to Na+ that is produced by a slight depolarisation. This action of local anaesthetics is due to their direct interaction with voltage-sensitive Na+ channels. Benzocaine is mainly hydroxylated in the metabolite para-aminobenzoic acid (PABA) that inhibits the action of sulphonamides.
5. Benzocaine is distributed in the body, crosses the placenta and is metabolised in the liver and in the plasma by non-specific cholinesterases. Benzocaine and its main metabolite (para-aminobenzoic acid) are excreted into urine.
6. Benzocaine appears as a moderately toxic compound after single administration. The acute intraperitoneal LD50 value was 216 mg/kg bw in mice. Benzocaine may induce methemoglobinemia in several species such as sheep, cats and dogs.
Factoy Superiority
We supply high quality TRANEXAMIC ACID API as well as its intermediates with over more than 10 years experience in production.
We have multiple grades on this API. We can supply BP, EP, JP, injection etc. With annual selling of more than 10 tons. It can be used in many aspects, such as in facial cream and in tabs etc. Either aspect we can provide accordingly materials.
We have full documentation support on this product, and it is on regular basis production. Feel free to contact us if you would develop this product or in search of an alternative source of provision.